Systemic Scleroderma

Autoimmune diseases and collagen diseases, such as systemic lupus erythematosus, dermatomyositis, scleroderma, and so on.

自身免疫性疾病及胶原性疾病, 如系统性红斑狼疮 、 皮肌炎 、 硬皮病等.

Systemic Scleroderma is also known as Systemic Sclerosis.

系统性硬皮病也看作系统性硬化症.

There was no cross reaction in the sera from 72 patients with dermatomyositis or polymyositis ( DM/ PM), from 48 patients with progressed systemic scleroderma ( PSS), and from 78 patients with mixed connective tissue disease ( MCTD).

对皮肌炎和多发性肌炎（DM/PM）72份、硬皮病（PSS）48份和混合性结缔组织病（MCTD）78份血清亦无交叉反应出现。

Anti ScL 70 antibody has been used as a diagnostic marker of systemic scleroderma. ScL 70 is DNA topoisomerase ⅰ.

系统性硬化病是一种自身免疫病，抗ScL70抗体是该病的标记性抗体，其抗原ScL70就是DNA拓扑异构酶Ⅰ。